Acne‎ ‎ ‎ Hormonal breakouts‎ ‎ ‎ Oiliness


A hormonal acne treatment

Topical spironolactone is used to manage acne.


Controls hormonal acne
Reduces sebum production
Calms inflammation


Have a question about how it works? Check out our other FAQs or drop us a message.

Topical spironolactone is a medication used to manage acne, especially hormonal breakouts.

Topical spironolactone works by blocking androgen receptors in the skin, reducing the effects of hormones that cause acne.

  • Hormonal Acne Control: Targets acne caused by hormonal imbalances.
  • Sebum Reduction: Decreases oil production in the skin.
  • Anti-Inflammatory: Helps reduce redness and swelling associated with acne.

Improvements typically appear at 12 weeks.

Common side effects include redness, dryness, and mild irritation. This is not a complete list of side effects and others may occur. Always read your Uncouth patient information leaflet prior to using your treatment.

Spironolactone should not be used during pregnancy whilst breastfeeding.


We use a technique called ‘compounding’ to carefully combine prescription ingredients with other actives. This allows us to tailor the concentration of certain ingredients to suit your skin. We are fully regulated by the General Pharmaceutical Council.

Our base contains natural moisturising factors and skin soothers such as aloe, vitamin E, triglycerides and hyaluronic acid. We are fragrance free and vegan and we don’t add any unnecessary ingredients.


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