Acne‎ ‎ ‎ Anti-Inflamatory‎ ‎ ‎ Anti-Ageing


A prescription retinoid that helps treat acne and improves texture.


Treats acne
Improves texture
Anti-ageing properties


Have a question about how it works? Check out our other FAQs or drop us a message.

Adapalene is a topical retinoid used primarily to treat acne by promoting cell turnover and reducing inflammation.

Adapalene works by binding to retinoic acid receptors in the skin, which helps to normalise the shedding of dead skin cells and prevent pores from becoming clogged.

  • Acne Treatment: Reduces the formation of acne lesions and certain types of acne scars.
  • Anti-Inflammatory: Decreases redness and swelling.
  • Anti-ageing: Adapalene can improve the appearance of fine lines and wrinkles.

Improvements can be seen within 4 weeks, with significant results typically appearing after 12 weeks.

Common side effects include dryness, redness, and peeling.

This is not a complete list of side effects and others may occur. Always read your Uncouth patient information leaflet prior to using your treatment.

Adapalene should not be used during pregnancy whilst breastfeeding.


We use a technique called ‘compounding’ to carefully combine prescription ingredients with other actives. This allows us to tailor the concentration of certain ingredients to suit your skin. We are fully regulated by the General Pharmaceutical Council.

Our base contains natural moisturising factors and skin soothers such as aloe, vitamin E, triglycerides and hyaluronic acid. We are fragrance free and vegan and we don’t add any unnecessary ingredients.


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